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ADHD Medication During Pregnancy and Breastfeeding
The decision to stop or continue ADHD medication during pregnancy and breastfeeding is a challenge for women suffering from the condition. There is a lack of information about how long-term exposure to these drugs can affect the foetus.
A study recently published in Molecular Psychiatry shows that children exposed to ADHD medication during utero do not develop neurological disorders such as impaired vision or hearing, febrile seizures, or IQ impairment. The authors acknowledge the need for more high-quality research.
Risk/Benefit Analysis
Pregnant women who use ADHD medications need to balance the benefits of taking them against potential risks to the fetus. Physicians do not have the information needed to provide clear recommendations however they can provide information about risks and benefits that aid pregnant women in making informed choices.
A study published in Molecular Psychiatry found that women who used ADHD medications during early pregnancy did not have a significantly increased risk of fetal cardiac malformations or major birth defects that are structural. Researchers conducted a large sample-based case control study to compare the incidence of structural defects that were major in infants who were born to mothers who took stimulants during pregnancy. Clinical geneticists and pediatric cardiologists reviewed the cases to ensure an accurate case classification and to minimize the chance of bias.
However, the researchers' study was not without its flaws. The researchers were not able to, in the first place, to separate the effects triggered by the medication from the disorder. This makes it difficult for researchers to establish whether the small associations observed among the groups that were exposed to medication use or affected by the presence of comorbidities. Additionally, the researchers did not examine the long-term outcomes of offspring.
The study showed that infants whose mothers took ADHD medication during pregnancy were at a slightly higher risk of admission to the neonatal care unit (NICU) as compared to those whose mothers did not use any medication during pregnancy, or had stopped taking their medication before or during pregnancy. The reason for this was central nervous system disorders. The increased risk of admission was not influenced by the stimulant medication used during pregnancy.
Women who were taking stimulant ADHD medications during pregnancy also had a higher risk of having to have caesarean sections or the baby was not scoring well on the Apgar scale (less than 7). These risks did not appear to be influenced by the type of medication that was used during pregnancy.
adult adhd medication suggest that the low risk associated with the use of ADHD medications during early pregnancy may be offset by the greater benefit for both mother and child from continued treatment for the woman's condition. Physicians should discuss this with their patients and, if possible, assist them in developing strategies for improving their coping skills that may minimize the negative impact of her condition on her daily life and relationships.
Medication Interactions
Many doctors are faced with the decision of whether to continue treatment or stop during pregnancy as more women are diagnosed with ADHD. Most of the time, these decisions are taken in the absence of clear and authoritative evidence either way, so physicians have to weigh their experience about their experiences, the experiences of other doctors, and what the research suggests about the subject, along with their own judgments for each individual patient.
The issue of risk to the infant can be difficult to determine. Many studies on this topic are based on observations rather than controlled research and their conclusions are often contradictory. Additionally, the majority of studies limit their analysis to live births, which can underestimate the severity of teratogenic effects that could result in abortion or termination of the pregnancy. The study presented in this journal club addresses these issues by looking at data from both live and deceased births.
The conclusion The conclusion: While some studies have shown an association between ADHD medications and the risk of certain birth defects, other studies have found no connection and the majority of studies show a neutral or even slightly negative effect. In every case, a careful evaluation of the benefits and risks is required.
For a lot of women with ADHD who suffer from ADHD, the decision to discontinue medication can be difficult, if not impossible. In a recent piece published in the Archives of Women's Mental Health by psychologist Jennifer Russell, she notes that stopping ADHD medications during pregnancy can increase depression and feelings of being isolated. Furthermore, a loss of medication can affect the ability to do work-related tasks and safely drive that are crucial aspects of daily life for many people suffering from ADHD.
She suggests that women who are unsure whether to take the medication or stop due to pregnancy educate family members, coworkers, and their friends about the condition, the effects on daily functioning, and the benefits of keeping the current treatment. It will also help a woman feel confident about her decision. Some medications can pass through the placenta. If a woman decides to not take her ADHD medication while breastfeeding, it's important to be aware that the medication could be transferred to the baby.
Birth Defects and Risk of
As the use of ADHD medication to treat the symptoms of attention deficit hyperactivity disorder (ADHD) grows as do concerns over the impact that these drugs could have on the fetuses. Recent research published in the journal Molecular Psychiatry has added to the body knowledge on this topic. Researchers used two massive data sets to study over 4.3 million pregnancy and determine if stimulant medication use increased birth defects. Although the risk overall remains low, the scientists found that exposure in the first trimester to ADHD medications was linked to an increased risk of certain heart defects like ventriculo-septal defects (VSD).
The researchers of the study did not discover any connection between the use of early medications and other congenital anomalies, such as facial deformities or club feet. The results are in the same vein as previous studies that showed an insignificant, but small increase in the number of cardiac malformations among women who began taking ADHD medication before the birth of their child. This risk increased in the later part of pregnancy, when many women decide to stop taking their ADHD medication.
Women who used ADHD medication in the first trimester of their pregnancy were also more likely to undergo caesarean sections, a low Apgar score after delivery and a baby who required breathing assistance during birth. The authors of the study were unable to remove bias in selection since they limited their study to women without other medical conditions that might have contributed to the findings.
Researchers hope their research will help doctors when they see pregnant women. The researchers recommend that, while discussing benefits and risks are important, the decision about whether to continue or stop medication should be based on the severity of each woman's ADHD symptoms and the needs of the woman.
The authors warn that, while stopping the medication is a possibility to consider, it is not recommended because of the high incidence of depression and mental health issues among women who are pregnant or recently gave birth. Additionally, the research suggests that women who decide to stop their medications are more likely to have a difficult time adapting to life without them following the baby's arrival.
Nursing
It can be a stressful experience to become a mom. Women with ADHD who have to manage their symptoms while attending doctor appointments and preparing for the arrival of a child and adapting to new routines in the home are often faced with a number of difficulties. As such, many women choose to continue taking their ADHD medications throughout pregnancy.
The risk for nursing infant is low because the majority of stimulant medication passes through breast milk at low levels. However, the amount of medication exposure to the newborn may differ based on the dosage, frequency it is taken and the time of the day it is administered. Additionally, different medications enter the baby’s system through the gastrointestinal tract or through breast milk. The effect on a newborn's health is not completely understood.
Some doctors may stop taking stimulant medications during a woman's pregnancy due to the lack of research. This is a difficult decision for the woman who must weigh the advantages of her medication against the potential risks to the foetus. Until more information is available, GPs should ask all pregnant patients about their experience with ADHD and if they are taking or planning to take medication during the perinatal period.
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A growing number of studies have proven that most women can safely continue their ADHD medication during pregnancy and breastfeeding. As a result, an increasing number of patients are choosing to do so and, in consultation with their doctor they have found that the benefits of keeping their current medication far outweigh any risks.
Women with ADHD who are planning to breastfeed should seek advice from a specialist psychiatrist before becoming pregnant. They should discuss their medication with their prescriber as well as the pros and cons for continuing treatment. This includes non-pharmacological strategies. Psychoeducation is also necessary to help pregnant women suffering from ADHD understand the symptoms and the underlying disorder. They should also be educated about treatment options and strengthen strategies for coping. This should be a multidisciplinary effort including obstetricians, GPs, and psychiatrists. Pregnancy counselling should include the discussion of a treatment plan for both the mother and child, and monitoring for signs of deterioration, and, if necessary, adjustments to the medication regimen.